该剧设定在《小丑回魂》的27年前，讲述小丑潘尼怀斯的起源故事。
故事讲述阿拉斯加州的Ennis迎来了漫长冬夜，在当地运作Tsalal北极科考站的8名男性消失得无影无踪。为了解决这起案件，Liz Danvers（朱迪·福斯特 饰）和Evangeline Navarro（卡莉·瑞斯 饰）这两位警探将不得不面对她们内心的黑暗，挖掘埋藏在永恒冰层下那些萦绕不去的真相。
好高骛远的陈春林（徐彬饰）在殡仪馆工作，意外发现一只可以穿越时空的打火机。他利用打火机投机钻营，回到过去寻找历史名人，再带历史文物回来倒卖牟利。然而，他冒险的行为却不慎改写了历史，还将自己卷入许多名人的命运轨迹。他不得不直面自己的失败，并重新寻找人生的意义。
奥斯卡·伊萨克饰演月光骑士/马克·史贝特具有分离性身份识别障碍，拥有性格迥异多重人格的他陷入埃及诸神的致命之战。马克‧史贝特是一名美国海军陆战队退役士兵，他成为一名雇佣兵，在埃及沙漠中死亡。埃及月亮之神孔苏复活了他并赐予力量。史贝特患有精神疾病，他的不同身份拥有性格迥异的人格。其中一个人格为温文儒雅的礼品店店员斯蒂芬·葛兰特（Steven Grant），长期遭受睡眠障碍困扰，甚至分不清梦境与现实。
Eminent Boston Psychiatrist, Frasier Crane, last seen gracing the bars of Cheers has left his life there to start afresh in Seattle. He now has a spot as a popular radio Psychiatrist, giving him the chance to spread words of wit and wisdom to the masses. He shares his apartment with his retired cop father, Martin, and his father's physical care assistant, Daphne Moon. Add in br...
The fifth-year residents return for the first day of a year that will make or break their careers: Meredith faces the consequences of tampering with Derek's clinical trial and is terminated at the hospital; April tries to step up to the plate as Chief Resident in the wake of a giant sinkhole in the middle of Seattle; and Cristina and Owen are still at odds over their drasticall...
